Modelling the micro-damage process zone during cortical bone fracture
نویسندگان
چکیده
منابع مشابه
Cortical Bone Fracture
The structural integrity of ‘‘hard’’ mineralized tissues such as bone is of great importance, especially because bone is the primary structural component of the body, serving as a protective load-bearing skeletal framework. As a structural material, bone is unique when compared with other engineering materials because of its wellknown capacity for self-repair and adaptation to changes in mechan...
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Parathyroid hormone-related protein (PTHrP) is widely expressed in the fibrous outer layer of the periosteum (PO), and the PTH/PTHrP type I receptor (PTHR1) is expressed in the inner PO cambial layer. The cambial layer gives rise to the PO osteoblasts (OBs) and osteoclasts (OCs) that model/remodel the cortical bone surface during development as well as during fracture healing. PTHrP has been im...
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• This is the author's version of a work that was accepted for publication in Computational Materials Science. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive vers...
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Although the mode I (tensile opening) fracture toughness has been the focus of most fracture mechanics studies of human cortical bone, bones in vivo are invariably loaded multiaxially. Consequently, an understanding of mixed-mode fracture is necessary to determine whether a mode I fracture toughness test provides the appropriate information to accurately quantify fracture risk. In this study, w...
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ژورنال
عنوان ژورنال: Engineering Fracture Mechanics
سال: 2020
ISSN: 0013-7944
DOI: 10.1016/j.engfracmech.2019.106811